AN OVERVIEW OF PELLETIZATION TECHNIQUES USED IN MULTIPARTICULATE DRUG DELIVERY SYSTEM

Multiple Unit Drug Delivery System: Pelletization Techniques

The present study aims at discussing the potential advantages of multiple unit dosage forms (pellets etc.) over the single unit dosage forms (tablets). Pelletization is a novel drug delivery system; a technique which converts fine powder particles into pellets. Review deals with the pellet and its various types of pelletization techniques like spheronization and extrusion, pelletization by laye...

An overview on multiparticulate drug delivery system: Pellets

Pellets can be defined as small, free flowing, spherical or semi-spherical solid units, typically from about 0.5 mm to 1.5 mm, and intended usually for oral administration, manufactured by the agglomerates of fine powders or granules of bulk drugs and excipients using appropriate processing equipment. Pellets can be prepared by many methods, the compaction and drug-layering being the most widel...

Multiparticulate chitosan-dispersed system for drug delivery.

A multiparticulate chitosan-dispersed system (CDS), which is composed of the drug reservoir and the drug release-regulating layer, was developed for drug delivery. The drug release-regulating layer is a mixture of water-insoluble polymer and chitosan powder. The drug is released from CDS pellets in all regions of the gastrointestinal tract (from the stomach to the colon). CDS pellets containing...

Pelletization Technique in Drug Delivery System- a Review

In present times, the pelletization technologies are giving much attention as they represent an efficient pathway for manufacture of new drug delivery system .It has good advantage over the conventional dosage form. Pelletization technique help in the formation of spherical beads or pellets having a diameter 0.5 -1.5 mm which can be eventually coated for preparation of modified release dosage f...

Multiparticulate Carriers for Controlled Oral Drug Delivery